Sage Bionetworks http://sagebase.org A Non Profit Biomedical Research Organization Tue, 11 Aug 2015 21:19:33 +0000 en-US hourly 1 http://wordpress.org/?v=4.2.4 Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection http://sagebase.org/combining-tumor-genome-simulation-with-crowdsourcing-to-benchmark-somatic-single-nucleotide-variant-detection-2/ http://sagebase.org/combining-tumor-genome-simulation-with-crowdsourcing-to-benchmark-somatic-single-nucleotide-variant-detection-2/#comments Tue, 11 Aug 2015 20:32:46 +0000 http://sagebase.org/?p=1894 A wonderful article in Nature Methods about the ICGC-TCGA DREAM Somatic Mutation Calling Challenge which includes a statement that reflects the power of DREAM Challenges: “… an ensemble of pipelines outperforms the best individual pipeline in all cases.” Read the full publication.

]]> http://sagebase.org/combining-tumor-genome-simulation-with-crowdsourcing-to-benchmark-somatic-single-nucleotide-variant-detection-2/feed/ 0 DREAM challenge uses crowd sourcing to test the state of the art in systems biomedicine http://sagebase.org/dream-challenge-uses-crowd-sourcing-to-test-the-state-of-the-art-in-systems-biomedicine/ http://sagebase.org/dream-challenge-uses-crowd-sourcing-to-test-the-state-of-the-art-in-systems-biomedicine/#comments Mon, 10 Aug 2015 20:47:42 +0000 http://sagebase.org/?p=1892 A very informative press release was issued with today’s Nature Biotechnology publication about the DREAM8 Toxicogenetics Challenge. Learn more.

]]> http://sagebase.org/dream-challenge-uses-crowd-sourcing-to-test-the-state-of-the-art-in-systems-biomedicine/feed/ 0 App-enabled trial participation: Tectonic shift or tepid rumble? http://sagebase.org/app-enabled-trial-participation-tectonic-shift-or-tepid-rumble/ http://sagebase.org/app-enabled-trial-participation-tectonic-shift-or-tepid-rumble/#comments Wed, 22 Jul 2015 19:45:02 +0000 http://sagebase.org/?p=1871 The most recent issue of Science Translational Medicine includes an editorial by Stephen Friend, President of Sage Bionetworks, that examines the role of apps in medical research. Read Full Article

]]> http://sagebase.org/app-enabled-trial-participation-tectonic-shift-or-tepid-rumble/feed/ 0 ISMB Presentation: How to Use DREAM Challenges and the Synapse Platform http://sagebase.org/ismb-presentation-how-to-use-dream-challenges-and-the-synapse-platform/ http://sagebase.org/ismb-presentation-how-to-use-dream-challenges-and-the-synapse-platform/#comments Wed, 08 Jul 2015 16:59:26 +0000 http://sagebase.org/?p=1840 AKES 01: Applied Knowledge in Building Networks for Translation: How to Use DREAM Challenge and Synapse Platform as a Research Strategy will be a session at the 23rd Annual International Conference on Intelligent Systems for Molecular Biology (ISMB) 14th European Conference on Computational Biology (ECCB) which is taking place in Dublin Ireland July 10-14.

]]> http://sagebase.org/ismb-presentation-how-to-use-dream-challenges-and-the-synapse-platform/feed/ 0 Up for a Challenge Launches! http://sagebase.org/up-for-a-challenge-launches/ http://sagebase.org/up-for-a-challenge-launches/#comments Wed, 24 Jun 2015 18:56:34 +0000 http://sagebase.org/?p=1829 Sage Bionetworks, in partnership with the National Cancer Institute’s (NCI) Division of Cancer Control and Population Sciences (DCCPS), launched a new prize competition this week, “Up For A Challenge (U4C) – Stimulating Innovation in Breast Cancer Genetic Epidemiology.” Learn more and register for the Challenge here.

Read a press release about the Challenge here.

]]> http://sagebase.org/up-for-a-challenge-launches/feed/ 0 2015 Paris Assembly http://sagebase.org/2015-paris-assembly/ http://sagebase.org/2015-paris-assembly/#comments Tue, 23 Jun 2015 17:48:20 +0000 http://sagebase.org/?p=1809 Paris Assembly 2015

The 2015 Paris Assembly based on the theme “Connecting Open Research, Open Education and Open Social Impact” was held on April 16-18, at the Institut Pasteur in Paris.  Video recordings of the Assembly are available online – Visit the Assembly page to learn more!

 

]]> http://sagebase.org/2015-paris-assembly/feed/ 0 Prize4Life, Sage Bionetworks and DREAM Launch an Open Science Challenge to Find Clues to Understanding Heterogeneity in Patients with Amyotrophic Lateral Sclerosis (ALS) http://sagebase.org/prize4life-sage-bionetworks-and-dream-launch-an-open-science-challenge-to-find-clues-to-understanding-heterogeneity-in-patients-with-amyotrophic-lateral-sclerosis-als/ http://sagebase.org/prize4life-sage-bionetworks-and-dream-launch-an-open-science-challenge-to-find-clues-to-understanding-heterogeneity-in-patients-with-amyotrophic-lateral-sclerosis-als/#comments Tue, 23 Jun 2015 17:14:22 +0000 http://sagebase.org/?p=1804 We are pleased to announce that the DREAM ALS Stratification Prize4Life Challenge, the first of the DREAM10 Challenges is now open for participation. This Challenge focuses on predicting the progression and survival of ALS patients.  The Challenge will leverage the PRO-ACT database of more than 8,000 cases as the Challenge training set, and feature several unpublished datasets that will be used for model validation. To learn more and join this Challenge, click here.
Additional information can be found here.

 

]]> http://sagebase.org/prize4life-sage-bionetworks-and-dream-launch-an-open-science-challenge-to-find-clues-to-understanding-heterogeneity-in-patients-with-amyotrophic-lateral-sclerosis-als/feed/ 0 ‘Crowdsourcing to Experts: The DREAM Challenges’ article in Biomedical Computation Review http://sagebase.org/crowdsourcing-to-experts-the-dream-challenges-article-in-biomedical-computation-review/ http://sagebase.org/crowdsourcing-to-experts-the-dream-challenges-article-in-biomedical-computation-review/#comments Thu, 18 Jun 2015 15:23:49 +0000 http://sagebase.org/?p=1800 Biomedical Computation Review, a journal focusing on Big Data to Knowledge Centers of Excellence, highlights DREAM including NCI-DREAM and ALS Challenges. Read the full article: Crowdsourcing to Experts: The DREAM Challenges.

]]> http://sagebase.org/crowdsourcing-to-experts-the-dream-challenges-article-in-biomedical-computation-review/feed/ 0 Prostate Cancer DREAM Challenge First Leaderboard Round Top Performers http://sagebase.org/prostate-cancer-dream-challenge-first-leaderboard-round-top-performers/ http://sagebase.org/prostate-cancer-dream-challenge-first-leaderboard-round-top-performers/#comments Thu, 04 Jun 2015 15:16:27 +0000 http://sagebase.org/?p=1791 The Prostate Cancer DREAM Challenge first leaderboard round is complete, and at the end of each of the leaderboard rounds we will be highlighting top performing teams. Along with the team profile, we asked a few DREAM related questions. Learn more about the top leaderboard teams.

]]> http://sagebase.org/prostate-cancer-dream-challenge-first-leaderboard-round-top-performers/feed/ 0 Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection http://sagebase.org/combining-tumor-genome-simulation-with-crowdsourcing-to-benchmark-somatic-single-nucleotide-variant-detection/ http://sagebase.org/combining-tumor-genome-simulation-with-crowdsourcing-to-benchmark-somatic-single-nucleotide-variant-detection/#comments Mon, 18 May 2015 18:23:26 +0000 http://sagebase.org/?p=1765 Nature logo

 

 

 

 

 

An interesting article in Nature about the ICGC-TCGA DREAM Somatic Mutation Calling Challenge.

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